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Study on the structure optimization and anti‐hepatitis B virus activity of novel human La protein inhibitor HBSC11

In our previous study, Methyl pyrazolo[1,5‐a] pyridine‐2‐carboxylate (HBSC11) was shown to combine with La protein, which conferred anti‐hepatitis B virus (HBV) effects. The purpose of this study was to optimize, synthesize, and evaluate the anti‐HBV activity of HBSC11. The methyl group of HBSC11 wa...

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Detalles Bibliográficos
Autores principales: Tong, Shuangmei, Pan, Jiaqian, Tang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771476/
https://www.ncbi.nlm.nih.gov/pubmed/31241178
http://dx.doi.org/10.1002/jmv.25528