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Functional muscle hypertrophy by increased insulin‐like growth factor 1 does not require dysferlin

INTRODUCTION: Dysferlin loss‐of‐function mutations cause muscular dystrophy, accompanied by impaired membrane repair and muscle weakness. Growth promoting strategies including insulin‐like growth factor 1 (IGF‐1) could provide benefit but may cause strength loss or be ineffective. The objective of t...

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Detalles Bibliográficos
Autores principales: Barton, Elisabeth R., Pham, Jennifer, Brisson, Becky K., Park, SooHyun, Smith, Lucas R., Liu, Min, Tian, Zuozhen, Hammers, David W., Vassilakos, Georgios, Sweeney, H. Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771521/
https://www.ncbi.nlm.nih.gov/pubmed/31323135
http://dx.doi.org/10.1002/mus.26641