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Toxoplasma gondii induces prolonged host epidermal growth factor receptor signalling to prevent parasite elimination by autophagy: Perspectives for in vivo control of the parasite

Toxoplasma gondii causes retinitis and encephalitis. Avoiding targeting by autophagosomes is key for its survival because T. gondii cannot withstand lysosomal degradation. During invasion of host cells, T. gondii triggers epidermal growth factor receptor (EGFR) signalling enabling the parasite to av...

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Detalles Bibliográficos
Autores principales: Lopez Corcino, Yalitza, Gonzalez Ferrer, Shekina, Mantilla, Luz Eliana, Trikeriotis, Sophia, Yu, Jin‐Sang, Kim, Steven, Hansen, Samuel, Portillo, Jose‐Andres C., Subauste, Carlos S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771541/
https://www.ncbi.nlm.nih.gov/pubmed/31290228
http://dx.doi.org/10.1111/cmi.13084