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IKAP—Identifying K mAjor cell Population groups in single-cell RNA-sequencing analysis

BACKGROUND: In single-cell RNA-sequencing analysis, clustering cells into groups and differentiating cell groups by differentially expressed (DE) genes are 2 separate steps for investigating cell identity. However, the ability to differentiate between cell groups could be affected by clustering. Thi...

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Detalles Bibliográficos
Autores principales: Chen, Yun-Ching, Suresh, Abhilash, Underbayev, Chingiz, Sun, Clare, Singh, Komudi, Seifuddin, Fayaz, Wiestner, Adrian, Pirooznia, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771546/
https://www.ncbi.nlm.nih.gov/pubmed/31574155
http://dx.doi.org/10.1093/gigascience/giz121