Biogenesis of lysosome‐related organelles complex‐1 (BORC) regulates late endosomal/lysosomal size through PIKfyve‐dependent phosphatidylinositol‐3,5‐bisphosphate

Mechanisms that control lysosomal function are essential for cellular homeostasis. Lysosomes adapt in size and number to cellular needs but little is known about the underlying molecular mechanism. We demonstrate that the late endosomal/lysosomal multimeric BLOC‐1‐related complex (BORC) regulates th...

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Detalles Bibliográficos
Autores principales: Yordanov, Teodor E., Hipolito, Victoria E. B., Liebscher, Gudrun, Vogel, Georg F., Stasyk, Taras, Herrmann, Caroline, Geley, Stephan, Teis, David, Botelho, Roberto J., Hess, Michael W., Huber, Lukas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons A/S 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771566/
https://www.ncbi.nlm.nih.gov/pubmed/31314175
http://dx.doi.org/10.1111/tra.12679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771566/
https://www.ncbi.nlm.nih.gov/pubmed/31314175
http://dx.doi.org/10.1111/tra.12679

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