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Enantio‐ and Diastereoselective Suzuki–Miyaura Coupling with Racemic Bicycles

Herein, we describe a rhodium‐catalyzed enantio‐ and diastereoselective Suzuki–Miyaura cross‐coupling between racemic fused bicyclic allylic chlorides and boronic acids. The highly stereoselective transformation allows for the coupling of aryl, heteroaryl, and alkenyl boronic acids and gives access...

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Detalles Bibliográficos
Autores principales: Goetzke, F. Wieland, Mortimore, Mike, Fletcher, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771587/
https://www.ncbi.nlm.nih.gov/pubmed/31246358
http://dx.doi.org/10.1002/anie.201906478