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Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1

Degeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature...

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Detalles Bibliográficos
Autores principales: Elshamly, Mahmoud, Kinslechner, Katharina, Grohs, Josef G., Weinmann, Daniela, Walzer, Sonja M., Windhager, Reinhard, Gabius, Hans‐Joachim, Toegel, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771593/
https://www.ncbi.nlm.nih.gov/pubmed/31115931
http://dx.doi.org/10.1002/jor.24351