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Galectins‐1 and ‐3 in Human Intervertebral Disc Degeneration: Non‐Uniform Distribution Profiles and Activation of Disease Markers Involving NF‐κB by Galectin‐1
Degeneration of the human intervertebral disc (IVD) is assumed to underlie severe clinical symptoms, in particular chronic back pain. Since adhesion/growth‐regulatory galectins are linked to arthritis/osteoarthritis pathogenesis by activating a pro‐degradative/‐inflammatory gene expression signature...
Autores principales: | Elshamly, Mahmoud, Kinslechner, Katharina, Grohs, Josef G., Weinmann, Daniela, Walzer, Sonja M., Windhager, Reinhard, Gabius, Hans‐Joachim, Toegel, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771593/ https://www.ncbi.nlm.nih.gov/pubmed/31115931 http://dx.doi.org/10.1002/jor.24351 |
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