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Essential role of IκB(NS) for in vivo CD4(+) T‐cell activation, proliferation, and Th1‐cell differentiation during Listeria monocytogenes infection in mice

Acquisition of effector functions in T cells is guided by transcription factors, including NF‐κB, that itself is tightly controlled by inhibitory proteins. The atypical NF‐κB inhibitor, IκB(NS,) is involved in the development of Th1, Th17, and regulatory T (Treg) cells. However, it remained unclear...

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Detalles Bibliográficos
Autores principales: Frentzel, Sarah, Katsoulis‐Dimitriou, Konstantinos, Jeron, Andreas, Schmitz, Ingo, Bruder, Dunja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771600/
https://www.ncbi.nlm.nih.gov/pubmed/31049948
http://dx.doi.org/10.1002/eji.201847961