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T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils

Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA‐DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which reduces allergen uptake by neutrophils. [...

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Detalles Bibliográficos
Autores principales: Samadi, Nazanin, Polak, Dominika, Kitzmüller, Claudia, Steinberger, Peter, Zlabinger, Gerhard J., Jahn‐Schmid, Beatrice, Bohle, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771661/
https://www.ncbi.nlm.nih.gov/pubmed/31332790
http://dx.doi.org/10.1002/eji.201848057