T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils

Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA‐DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which reduces allergen uptake by neutrophils. [...

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Detalles Bibliográficos
Autores principales: Samadi, Nazanin, Polak, Dominika, Kitzmüller, Claudia, Steinberger, Peter, Zlabinger, Gerhard J., Jahn‐Schmid, Beatrice, Bohle, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771661/
https://www.ncbi.nlm.nih.gov/pubmed/31332790
http://dx.doi.org/10.1002/eji.201848057
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author Samadi, Nazanin
Polak, Dominika
Kitzmüller, Claudia
Steinberger, Peter
Zlabinger, Gerhard J.
Jahn‐Schmid, Beatrice
Bohle, Barbara
author_facet Samadi, Nazanin
Polak, Dominika
Kitzmüller, Claudia
Steinberger, Peter
Zlabinger, Gerhard J.
Jahn‐Schmid, Beatrice
Bohle, Barbara
author_sort Samadi, Nazanin
collection PubMed
description Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA‐DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which reduces allergen uptake by neutrophils. [Image: see text]
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spelling pubmed-67716612019-10-07 T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils Samadi, Nazanin Polak, Dominika Kitzmüller, Claudia Steinberger, Peter Zlabinger, Gerhard J. Jahn‐Schmid, Beatrice Bohle, Barbara Eur J Immunol Letter to the Editor Activated allergen‐specific Th2 and Th1 cells release cytokines that transform neutrophils into functional APCs characterized by the expression of HLA‐DR and CD58 as well as enhanced survival and antigen uptake, irrespectively of the presence of IL‐10, which reduces allergen uptake by neutrophils. [Image: see text] John Wiley and Sons Inc. 2019-08-06 2019-09 /pmc/articles/PMC6771661/ /pubmed/31332790 http://dx.doi.org/10.1002/eji.201848057 Text en © 2019 The Authors. European Journal of Immunology published by WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Samadi, Nazanin
Polak, Dominika
Kitzmüller, Claudia
Steinberger, Peter
Zlabinger, Gerhard J.
Jahn‐Schmid, Beatrice
Bohle, Barbara
T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title_full T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title_fullStr T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title_full_unstemmed T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title_short T‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
title_sort t‐cell‐derived cytokines enhance the antigen‐presenting capacity of human neutrophils
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771661/
https://www.ncbi.nlm.nih.gov/pubmed/31332790
http://dx.doi.org/10.1002/eji.201848057
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