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Meta‐analysis of massively parallel reporter assays enables prediction of regulatory function across cell types

Deciphering the potential of noncoding loci to influence gene regulation has been the subject of intense research, with important implications in understanding genetic underpinnings of human diseases. Massively parallel reporter assays (MPRAs) can measure regulatory activity of thousands of DNA sequ...

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Detalles Bibliográficos
Autores principales: Kreimer, Anat, Yan, Zhongxia, Ahituv, Nadav, Yosef, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771677/
https://www.ncbi.nlm.nih.gov/pubmed/31131957
http://dx.doi.org/10.1002/humu.23820