Cargando…

Sulfasalazine decreases mouse cortical hyperexcitability

OBJECTIVE: Currently prescribed antiepileptic drugs (AEDs) are ineffective in treating approximately 30% of epilepsy patients. Sulfasalazine (SAS) is an US Food and Drug Administration (FDA)–approved drug for the treatment of Crohn disease that has been shown to inhibit the cystine/glutamate antipor...

Descripción completa

Detalles Bibliográficos
Autores principales: Alcoreza, Oscar, Tewari, Bhanu P., Bouslog, Allison, Savoia, Andrew, Sontheimer, Harald, Campbell, Susan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771750/
https://www.ncbi.nlm.nih.gov/pubmed/31211419
http://dx.doi.org/10.1111/epi.16073