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Alpha‐synuclein at the nexus of genes and environment: the impact of environmental enrichment and stress on brain health and disease
Accumulation of alpha‐synuclein protein aggregates is the hallmark neuropathologic feature of synucleinopathies such as Parkinson’s disease. Rare point mutations and multiplications in SNCA, the gene encoding alpha‐synuclein, as well as other genetic alterations are linked to familial Parkinson’s di...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771760/ https://www.ncbi.nlm.nih.gov/pubmed/31165472 http://dx.doi.org/10.1111/jnc.14787 |