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Alpha‐synuclein at the nexus of genes and environment: the impact of environmental enrichment and stress on brain health and disease

Accumulation of alpha‐synuclein protein aggregates is the hallmark neuropathologic feature of synucleinopathies such as Parkinson’s disease. Rare point mutations and multiplications in SNCA, the gene encoding alpha‐synuclein, as well as other genetic alterations are linked to familial Parkinson’s di...

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Detalles Bibliográficos
Autores principales: Wassouf, Zinah, Schulze‐Hentrich, Julia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771760/
https://www.ncbi.nlm.nih.gov/pubmed/31165472
http://dx.doi.org/10.1111/jnc.14787