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Cerebral bioenergetic differences measured by phosphorus‐31 magnetic resonance spectroscopy between bipolar disorder and healthy subjects living in two different regions suggesting possible effects of altitude

AIM: Increased oxidative stress in cerebral mitochondria may follow exposure to the systemic hypobaric hypoxia associated with residing at higher altitudes. Because mitochondrial dysfunction is implicated in bipolar disorder (BD) pathophysiology, this may impact the cerebral bioenergetics in BD. In...

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Detalles Bibliográficos
Autores principales: Hwang, Jaeuk, DeLisi, Lynn E., Öngür, Dost, Riley, Colin, Zuo, Chun, Shi, Xianfeng, Sung, Young‐Hoon, Kondo, Douglas, Kim, Tae‐Suk, Villafuerte, Rosemond, Smedberg, Diane, Yurgelun‐Todd, Deborah, Renshaw, Perry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771782/
https://www.ncbi.nlm.nih.gov/pubmed/31125152
http://dx.doi.org/10.1111/pcn.12893