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Artificially Linked Ubiquitin Dimers Characterised Structurally and Dynamically by NMR Spectroscopy

As one of the most prevalent post‐translational modifications in eukaryotic cells, ubiquitylation plays vital roles in many cellular processes, such as protein degradation, DNA metabolism, and cell differentiation. Substrate proteins can be tagged by distinct types of polymeric ubiquitin (Ub) chains...

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Detalles Bibliográficos
Autores principales: Zhao, Xiaohui, Mißun, Maite, Schneider, Tobias, Müller, Franziska, Lutz, Joachim, Scheffner, Martin, Marx, Andreas, Kovermann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771822/
https://www.ncbi.nlm.nih.gov/pubmed/30920720
http://dx.doi.org/10.1002/cbic.201900146