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Targeting the complexity of Src signalling in the tumour microenvironment of pancreatic cancer: from mechanism to therapy

Pancreatic cancer, a disease with extremely poor prognosis, has been notoriously resistant to virtually all forms of treatment. The dynamic crosstalk that occurs between tumour cells and the surrounding stroma, frequently mediated by intricate Src/FAK signalling, is increasingly recognised as a key...

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Detalles Bibliográficos
Autores principales: Parkin, Ashleigh, Man, Jennifer, Timpson, Paul, Pajic, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771888/
https://www.ncbi.nlm.nih.gov/pubmed/31330086
http://dx.doi.org/10.1111/febs.15011