A Mild Synthesis of Bicyclic Alkoxyoxazolium Salts from Proline and Pipecolic Acid Derivatives

A regio‐ and chemoselective preparation of bicyclic alkoxyoxazolium salts from amide derivatives of proline and pipecolic acid by electrophilic amide activation is reported. Mechanistic NMR experiments suggest an unusual role for the base and highlight the effect of substitution pattern of the subst...

Descripción completa

Detalles Bibliográficos
Autores principales: Spinozzi, Eleonora, Bauer, Adriano, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771909/
https://www.ncbi.nlm.nih.gov/pubmed/31598092
http://dx.doi.org/10.1002/ejoc.201900985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6771909/
https://www.ncbi.nlm.nih.gov/pubmed/31598092
http://dx.doi.org/10.1002/ejoc.201900985

Ejemplares similares