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Early malaria infection, dysregulation of angiogenesis, metabolism and inflammation across pregnancy, and risk of preterm birth in Malawi: A cohort study

BACKGROUND: Malaria in pregnancy is associated with adverse birth outcomes. However, the underlying mechanisms remain poorly understood. Tight regulation of angiogenic, metabolic, and inflammatory pathways are essential for healthy pregnancies. We hypothesized that malaria disrupts these pathways le...

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Detalles Bibliográficos
Autores principales: Elphinstone, Robyn E., Weckman, Andrea M., McDonald, Chloe R., Tran, Vanessa, Zhong, Kathleen, Madanitsa, Mwayiwawo, Kalilani-Phiri, Linda, Khairallah, Carole, Taylor, Steve M., Meshnick, Steven R., Mwapasa, Victor, ter Kuile, Feiko O., Conroy, Andrea L., Kain, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772002/
https://www.ncbi.nlm.nih.gov/pubmed/31574087
http://dx.doi.org/10.1371/journal.pmed.1002914