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Four‐jointed knock‐out delays renal failure in an ADPKD model with kidney injury

Autosomal Dominant Polycystic Kidney Disease is characterised by the development of fluid‐filled cysts in the kidneys which lead to end‐stage renal disease (ESRD). In the majority of cases, the disease is caused by a mutation in the Pkd1 gene. In a previous study, we demonstrated that renal injury c...

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Detalles Bibliográficos
Autores principales: Formica, Chiara, Happé, Hester, Veraar, Kimberley AM, Vortkamp, Andrea, Scharpfenecker, Marion, McNeill, Helen, Peters, Dorien JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772084/
https://www.ncbi.nlm.nih.gov/pubmed/31038742
http://dx.doi.org/10.1002/path.5286