RNAi-mediated depletion of the NSL complex subunits leads to abnormal chromosome segregation and defective centrosome duplication in Drosophila mitosis

The Drosophila Nonspecific Lethal (NSL) complex is a major transcriptional regulator of housekeeping genes. It contains at least seven subunits that are conserved in the human KANSL complex: Nsl1/Wah (KANSL1), Dgt1/Nsl2 (KANSL2), Rcd1/Nsl3 (KANSL3), Rcd5 (MCRS1), MBD-R2 (PHF20), Wds (WDR5) and Mof (...

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Detalles Bibliográficos
Autores principales: Pavlova, Gera A., Popova, Julia V., Andreyeva, Evgeniya N., Yarinich, Lyubov A., Lebedev, Mikhail O., Razuvaeva, Alyona V., Dubatolova, Tatiana D., Oshchepkova, Anastasiya L., Pellacani, Claudia, Somma, Maria Patrizia, Pindyurin, Alexey V., Gatti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772098/
https://www.ncbi.nlm.nih.gov/pubmed/31527906
http://dx.doi.org/10.1371/journal.pgen.1008371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772098/
https://www.ncbi.nlm.nih.gov/pubmed/31527906
http://dx.doi.org/10.1371/journal.pgen.1008371

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