Highly Enantioselective Catalytic Addition of Grignard Reagents to N‐Heterocyclic Acceptors

General methods to prepare chiral N‐heterocyclic molecular scaffolds are greatly sought after because of their significance in medicinal chemistry. Described here is the first general catalytic methodology to access a wide variety of chiral 2‐ and 4‐substituted tetrahydro‐quinolones, dihydro‐4‐pyrid...

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Detalles Bibliográficos
Autores principales: Guo, Yafei, Harutyunyan, Syuzanna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772156/
https://www.ncbi.nlm.nih.gov/pubmed/31257687
http://dx.doi.org/10.1002/anie.201906237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772156/
https://www.ncbi.nlm.nih.gov/pubmed/31257687
http://dx.doi.org/10.1002/anie.201906237

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