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An Enamide‐Based Domino Reaction for a Highly Stereoselective Synthesis of Tetrahydropyrans
A novel method for the highly stereoselective synthesis of tetrahydropyrans is reported. This domino reaction is based on a twofold addition of enamides to aldehydes followed by a subsequent cyclization and furnishes fully substituted tetrahydropyrans in high yields. Three new σ‐bonds and five conti...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6772187/ https://www.ncbi.nlm.nih.gov/pubmed/31298800 http://dx.doi.org/10.1002/anie.201907565 |