TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

The faithful segregation of eukaryotic chromosomes in mitosis requires that the genome be duplicated completely prior to anaphase. However, cells with large genomes sometimes fail to complete replication during interphase and instead enter mitosis with regions of incompletely replicated DNA. These r...

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Detalles Bibliográficos
Autores principales: Sonneville, Remi, Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian D, Labib, Karim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773462/
https://www.ncbi.nlm.nih.gov/pubmed/31545170
http://dx.doi.org/10.7554/eLife.48686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773462/
https://www.ncbi.nlm.nih.gov/pubmed/31545170
http://dx.doi.org/10.7554/eLife.48686

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