Cargando…

Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization

Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial interaction between gametes, additional molecules necessary for sperm:egg fusion on both the sperm and the oocyte remain to be defined. Here, we show that phosphatidylserine (PtdSer) is exposed on the...

Descripción completa

Detalles Bibliográficos
Autores principales: Rival, Claudia M., Xu, Wenhao, Shankman, Laura S., Morioka, Sho, Arandjelovic, Sanja, Lee, Chang Sup, Wheeler, Karen M., Smith, Ryan P., Haney, Lisa B., Isakson, Brant E., Purcell, Scott, Lysiak, Jeffrey J., Ravichandran, Kodi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773685/
https://www.ncbi.nlm.nih.gov/pubmed/31575859
http://dx.doi.org/10.1038/s41467-019-12406-z