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Phosphatidylserine on viable sperm and phagocytic machinery in oocytes regulate mammalian fertilization
Fertilization is essential for species survival. Although Izumo1 and Juno are critical for initial interaction between gametes, additional molecules necessary for sperm:egg fusion on both the sperm and the oocyte remain to be defined. Here, we show that phosphatidylserine (PtdSer) is exposed on the...
Autores principales: | Rival, Claudia M., Xu, Wenhao, Shankman, Laura S., Morioka, Sho, Arandjelovic, Sanja, Lee, Chang Sup, Wheeler, Karen M., Smith, Ryan P., Haney, Lisa B., Isakson, Brant E., Purcell, Scott, Lysiak, Jeffrey J., Ravichandran, Kodi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773685/ https://www.ncbi.nlm.nih.gov/pubmed/31575859 http://dx.doi.org/10.1038/s41467-019-12406-z |
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