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Scribble co-operatively binds multiple α(1D)-adrenergic receptor C-terminal PDZ ligands

Many G protein-coupled receptors (GPCRs) are organized as dynamic macromolecular complexes in human cells. Unraveling the structural determinants of unique GPCR complexes may identify unique protein:protein interfaces to be exploited for drug development. We previously reported α(1D)-adrenergic rece...

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Detalles Bibliográficos
Autores principales: Janezic, Eric M., Harris, Dorathy-Ann, Dinh, Diana, Lee, Kyung-Soon, Stewart, Aaron, Hinds, Thomas R., Hsu, Peter L., Zheng, Ning, Hague, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773690/
https://www.ncbi.nlm.nih.gov/pubmed/31575922
http://dx.doi.org/10.1038/s41598-019-50671-6