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Scribble co-operatively binds multiple α(1D)-adrenergic receptor C-terminal PDZ ligands
Many G protein-coupled receptors (GPCRs) are organized as dynamic macromolecular complexes in human cells. Unraveling the structural determinants of unique GPCR complexes may identify unique protein:protein interfaces to be exploited for drug development. We previously reported α(1D)-adrenergic rece...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773690/ https://www.ncbi.nlm.nih.gov/pubmed/31575922 http://dx.doi.org/10.1038/s41598-019-50671-6 |