Cargando…

Antileukemic activity of novel adenosine derivatives

The present study investigated the effect of cladribine (CLA) and six of its derivatives containing a formamidine group at position 6 (CLA-FDM, CLA-FPAZ, CLA-FPIR, CLA-FPIP, CLA-FHEX, and CLA-FMOR) on acute promyelocytic, lymphoblastic, and acute monocytic leukemia cells. The role of ATR kinase in d...

Descripción completa

Detalles Bibliográficos
Autores principales: Poczta, Anastazja, Rogalska, Aneta, Łukawska, Małgorzata, Marczak, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773697/
https://www.ncbi.nlm.nih.gov/pubmed/31575977
http://dx.doi.org/10.1038/s41598-019-50509-1