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Inactivated alpha toxin from Clostridium novyi type B in nano-emulsion protect partially protects Swiss mice from lethal alpha toxin challenge

Nano-emulsions are promising carriers for antigen delivery. Here, we evaluated the efficacy of a water-oil nano-emulsion containing concentrated, inactivated Clostridium novyi (C. novyi) type B supernatant culture (nano-iCnB) in protecting Swiss mice against a lethal dose of alpha toxin concentrated...

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Detalles Bibliográficos
Autores principales: Felix, Mellanie Karoline C., Deusdará, Tullio T., Santos, Lucas Samuel S., Aguiar, Raimundo Wagner S., Corrêa, Roberto Franco T., Brandi, Igor V., Sobrinho, Eliane M., Ribeiro, Bergmann M., Mariúba, Luis André M., Nogueira, Paulo A., Costa, Kattyanne S., Viana, Kelvinson F., Cangussu, Alex Sander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773766/
https://www.ncbi.nlm.nih.gov/pubmed/31575942
http://dx.doi.org/10.1038/s41598-019-50683-2