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Differential Modulation of I(K) and I(Ca,L) Channels in High-Fat Diet-Induced Obese Guinea Pig Atria

Obesity mechanisms that make atrial tissue vulnerable to arrhythmia are poorly understood. Voltage-dependent potassium (I(K), I(Kur), and I(K1)) and L-type calcium currents (I(Ca,L)) are electrically relevant and represent key substrates for modulation in obesity. We investigated whether electrical...

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Detalles Bibliográficos
Autores principales: Martinez-Mateu, Laura, Saiz, Javier, Aromolaran, Ademuyiwa S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773813/
https://www.ncbi.nlm.nih.gov/pubmed/31607952
http://dx.doi.org/10.3389/fphys.2019.01212