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Modeling the Distribution of Diprotic Basic Drugs in Liposomal Systems: Perspectives on Malaria Nanotherapy

Understanding how polyprotic compounds distribute within liposome (LP) suspensions is of major importance to design effective drug delivery strategies. Advances in this research field led to the definition of LP-based active drug encapsulation methods driven by transmembrane pH gradients with eviden...

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Detalles Bibliográficos
Autores principales: Moles, Ernest, Kavallaris, Maria, Fernàndez-Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773836/
https://www.ncbi.nlm.nih.gov/pubmed/31611785
http://dx.doi.org/10.3389/fphar.2019.01064