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High-affinity Cu(I) chelator PSP-2 as potential anti-angiogenic agent

Copper is an essential trace metal that has been implicated in angiogenesis, the formation of new blood vessels. As tumor growth relies on establishing a functional capillary network for blood supply, copper chelation therapy may hold promise as an anti-cancer strategy by suppressing angiogenesis. T...

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Detalles Bibliográficos
Autores principales: Heuberger, Dorothea M., Harankhedkar, Shefali, Morgan, Thomas, Wolint, Petra, Calcagni, Maurizio, Lai, Barry, Fahrni, Christoph J., Buschmann, Johanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773859/
https://www.ncbi.nlm.nih.gov/pubmed/31575910
http://dx.doi.org/10.1038/s41598-019-50494-5