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The Effects of Thymoquinone on Viability, and Anti-apoptotic Factors (BCL-XL, BCL-2, MCL-1) in Prostate Cancer (PC3) Cells: An In Vitro and Computer-Simulated Environment Study

Purpose: Since active plant ingredients can induce apoptosis in many tumors, in this study we evaluate the apoptotic effects of thymoquinone (TQ) on PC3 cells. Also, we predicted the interaction of TQ with BCL-XL, BCL-2, and MCL-1anti-apoptotic factors by computer-simulated environment. Methods: PC3...

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Detalles Bibliográficos
Autores principales: Saffari_Chaleshtori, Javad, Heidari-Sureshjani, Ehsan, Moradi, Fahimeh, Heidarian, Esfandiar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773927/
https://www.ncbi.nlm.nih.gov/pubmed/31592099
http://dx.doi.org/10.15171/apb.2019.058