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Synergetic Impact of Combined 5-Fluorouracil and Rutin on Apoptosis in PC3 Cancer Cells through the Modulation of P53 Gene Expression

Purpose: Prostate cancer is as far the most prevalent male cancer. Rutin (a glycoside from quercetin flavonoid) displays antioxidant activity leading to cell apoptosis. Combined effects of rutin with the widely used anti-cancer drug, 5-fluorouracil (5-FU), on prostate cancer cell line (PC3) was inve...

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Detalles Bibliográficos
Autores principales: Satari, Atefeh, Amini, Sayed Asadollah, Raeisi, Elham, Lemoigne, Yves, Heidarian, Esfandiar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773939/
https://www.ncbi.nlm.nih.gov/pubmed/31592435
http://dx.doi.org/10.15171/apb.2019.055