Positive Effects of PI3K/Akt Signaling Inhibition on PTEN and P53 in Prevention of Acute Lymphoblastic Leukemia Tumor Cells

Purpose: The PI3K/Akt signaling pathway regulates cell growth, proliferation and viability in hematopoietic cells. This pathway always dysregulates in acute lymphoblastic leukemia (ALL). PTEN and P53 are tumor suppressor genes correlated with PI3K/Akt signaling pathway, and both have a tight link in...

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Detalles Bibliográficos
Autores principales: Naderali, Elahe, Valipour, Behnaz, Khaki, Amir Afshin, Soleymani Rad, Jafar, Alihemmati, Alireza, Rahmati, Mohammad, Nozad Charoudeh, Hojjatollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773944/
https://www.ncbi.nlm.nih.gov/pubmed/31592121
http://dx.doi.org/10.15171/apb.2019.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773944/
https://www.ncbi.nlm.nih.gov/pubmed/31592121
http://dx.doi.org/10.15171/apb.2019.056

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