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Competitive Interactions between PIRT, the Cold Sensing Ion Channel TRPM8, and PIP(2) Suggest a Mechanism for Regulation
TRPM8 is a member of the transient receptor potential ion channel family where it functions as a cold and pain sensor in humans and other higher organisms. Previous studies show that TRPM8 requires the signaling phosphoinositide lipid PIP(2) to function. TRPM8 function is further regulated by other...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773951/ https://www.ncbi.nlm.nih.gov/pubmed/31575973 http://dx.doi.org/10.1038/s41598-019-49912-5 |