Effects of the Novel IDO Inhibitor DWG-1036 on the Behavior of Male and Female 3xTg-AD Mice

The kynurenine pathway metabolizes tryptophan into nicotinamide adenine dinucleotide, producing a number of intermediary metabolites, including 3-hydroxy kynurenine and quinolinic acid, which are involved in the neurodegenerative mechanisms that underlie Alzheimer’s disease (AD). Indolamine 2,3-diox...

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Detalles Bibliográficos
Autores principales: Fertan, Emre, Stover, Kurt R.J., Brant, Michael G., Stafford, Paul M., Kelly, Brendan, Diez-Cecilia, Elena, Wong, Aimée A., Weaver, Donald F., Brown, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773979/
https://www.ncbi.nlm.nih.gov/pubmed/31607909
http://dx.doi.org/10.3389/fphar.2019.01044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6773979/
https://www.ncbi.nlm.nih.gov/pubmed/31607909
http://dx.doi.org/10.3389/fphar.2019.01044

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