Topoisomerases and cancer chemotherapy: recent advances and unanswered questions

DNA topoisomerases are enzymes that catalyze changes in the torsional and flexural strain of DNA molecules. Earlier studies implicated these enzymes in a variety of processes in both prokaryotes and eukaryotes, including DNA replication, transcription, recombination, and chromosome segregation. Stud...

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Detalles Bibliográficos
Autores principales: Bjornsti, Mary-Ann, Kaufmann, Scott H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774054/
https://www.ncbi.nlm.nih.gov/pubmed/31602296
http://dx.doi.org/10.12688/f1000research.20201.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774054/
https://www.ncbi.nlm.nih.gov/pubmed/31602296
http://dx.doi.org/10.12688/f1000research.20201.1

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