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Topoisomerases and cancer chemotherapy: recent advances and unanswered questions
DNA topoisomerases are enzymes that catalyze changes in the torsional and flexural strain of DNA molecules. Earlier studies implicated these enzymes in a variety of processes in both prokaryotes and eukaryotes, including DNA replication, transcription, recombination, and chromosome segregation. Stud...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774054/ https://www.ncbi.nlm.nih.gov/pubmed/31602296 http://dx.doi.org/10.12688/f1000research.20201.1 |