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Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells

Diosgenin (Di), a steroidal sapogenin derived from plants, has been shown to exert anticancer effects in preclinical studies. Using Di as a starting material, various Di derivatives were designed and synthesized, aiming to discover new steroid-based antitumor agents. In this work, we synthesized sev...

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Detalles Bibliográficos
Autores principales: Xu, Liang, Xu, Dekang, Li, Ziying, Gao, Yu, Chen, Haijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774070/
https://www.ncbi.nlm.nih.gov/pubmed/31598460
http://dx.doi.org/10.3762/bjnano.10.189