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Mechanisms of IFNalpha-1a-Induced Apoptosis in a Laryngeal Cancer Cell Line

BACKGROUND: Interferon alpha (IFNalpha) exerts its anti-proliferative effect on many human cancers. Among the 13 subtypes of human IFNalpha, IFNalpha-1 subtype has 2 variants, named IFNalpha-1a and IFNalpha-1b, that differ from each other in only 1 amino acid, at residue 114. However, the mechanism...

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Detalles Bibliográficos
Autores principales: Xin, Xiao-Lei, Zhang, Ran, Yuan, Xiao-Mei, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774267/
https://www.ncbi.nlm.nih.gov/pubmed/31542790
http://dx.doi.org/10.12659/MSM.917097