Activation of the Kinin B1 Receptor by Its Agonist Reduces Melanoma Metastasis by Playing a Dual Effect on Tumor Cells and Host Immune Response

Metastatic melanoma is an aggressive type of skin cancer leading half of the patients to death within 8–10 months after diagnosis. Kinins are peptides that interact with B1 and B2 receptors playing diverse biological roles. We investigated whether treatment with B1 receptor agonist, des-Arg(9)-brady...

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Detalles Bibliográficos
Autores principales: Maria, Andrea Gutierrez, Dillemburg-Pilla, Patrícia, Durand, Marina de Toledo, Floriano, Elaine Medeiros, Manfiolli, Adriana Oliveira, Ramos, Simone Gusmão, Pesquero, João Bosco, Nahmias, Clara, Costa-Neto, Claudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774293/
https://www.ncbi.nlm.nih.gov/pubmed/31607931
http://dx.doi.org/10.3389/fphar.2019.01106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774293/
https://www.ncbi.nlm.nih.gov/pubmed/31607931
http://dx.doi.org/10.3389/fphar.2019.01106

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