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Chemoenzymatic Synthesis of Sialic Acid Derivatives Using Immobilized N‐Acetylneuraminate Lyase in a Continuous Flow Reactor

The synthesis of N‐acetylneuraminic acid (Neu5Ac) derivatives is drawing more and more attention in glycobiology research because of the important role of sialic acids in e. g. cancer, bacterial, and healthy cells. Chemical preparation of these carbohydrates typically relies on multistep synthetic p...

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Detalles Bibliográficos
Autores principales: Bloemendal, Victor R. L. J., Moons, Sam J., Heming, Jurriaan J. A., Chayoua, Mohamed, Niesink, Olaf, van Hest, Jan C. M., Boltje, Thomas J., Rutjes, Floris P. J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774325/
https://www.ncbi.nlm.nih.gov/pubmed/31598119
http://dx.doi.org/10.1002/adsc.201900146