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Chemoenzymatic Synthesis of Sialic Acid Derivatives Using Immobilized N‐Acetylneuraminate Lyase in a Continuous Flow Reactor
The synthesis of N‐acetylneuraminic acid (Neu5Ac) derivatives is drawing more and more attention in glycobiology research because of the important role of sialic acids in e. g. cancer, bacterial, and healthy cells. Chemical preparation of these carbohydrates typically relies on multistep synthetic p...
Autores principales: | Bloemendal, Victor R. L. J., Moons, Sam J., Heming, Jurriaan J. A., Chayoua, Mohamed, Niesink, Olaf, van Hest, Jan C. M., Boltje, Thomas J., Rutjes, Floris P. J. T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774325/ https://www.ncbi.nlm.nih.gov/pubmed/31598119 http://dx.doi.org/10.1002/adsc.201900146 |
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