Synthesis and Evaluations of “1,4‐Triazolyl Combretacoumarins” and Desmethoxy Analogs

1,4‐Triazolyl combretacoumarins have been prepared by linking the trimethoxyarene unit of combretastatin A4 with coumarins, via a 1,2,3‐triazole. For this, 4‐azidocoumarins were accessed by a sequential two‐step, one‐pot reaction of 4‐hydroxycoumarins with (benzotriazol‐1‐yloxy)tris(dimethylamino)ph...

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Detalles Bibliográficos
Autores principales: Khandaker, Tashrique A., Hess, Jessica D., Aguilera, Renato, Andrei, Graciela, Snoeck, Robert, Schols, Dominique, Pradhan, Padmanava, Lakshman, Mahesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774347/
https://www.ncbi.nlm.nih.gov/pubmed/31579393
http://dx.doi.org/10.1002/ejoc.201900569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774347/
https://www.ncbi.nlm.nih.gov/pubmed/31579393
http://dx.doi.org/10.1002/ejoc.201900569

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