ACOX1 destabilizes p73 to suppress intrinsic apoptosis pathway and regulates sensitivity to doxorubicin in lymphoma cells

Lymphoma is one of the most curable types of cancer. However, drug resistance is the main challenge faced in lymphoma treatment. Peroxisomal acyl-CoA oxidase 1 (ACOX1) is the rate-limiting enzyme in fatty acid β-oxidation. Deregulation of ACOX1 has been linked to peroxisomal disorders and carcinogen...

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Detalles Bibliográficos
Autores principales: Zheng, Fei-Meng, Chen, Wang-Bing, Qin, Tao, Lv, Li-Na, Feng, Bi, Lu, Yan-Ling, Li, Zuo-Quan, Wang, Xiao-Chao, Tao, Li-Ju, Li, Hong-Wen, Li, Shu-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774419/
https://www.ncbi.nlm.nih.gov/pubmed/31401980
http://dx.doi.org/10.5483/BMBRep.2019.52.9.094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774419/
https://www.ncbi.nlm.nih.gov/pubmed/31401980
http://dx.doi.org/10.5483/BMBRep.2019.52.9.094

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