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LRRK2 and membrane trafficking: nexus of Parkinson’s disease

Recent evidence from genetics, animal model systems and biochemical studies suggests that defects in membrane trafficking play an important part in the pathophysiology of Parkinson’s disease (PD). Mutations in leucine-rich repeat kinase 2 (LRRK2) constitute the most frequent genetic cause of both fa...

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Detalles Bibliográficos
Autores principales: Hur, Eun-Mi, Jang, Eun-Hae, Jeong, Ga Ram, Lee, Byoung Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774422/
https://www.ncbi.nlm.nih.gov/pubmed/31383252
http://dx.doi.org/10.5483/BMBRep.2019.52.9.186