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Develop and Field Evolution of Single Tube Nested PCR, SYBRGreen PCR Methods, for the Diagnosis of Leprosy in Paraffin-embedded Formalin Fixed Tissues in Yunnan Province, a Hyper endemic Area of Leprosy in China

BACKGROUND: Detection and pathology analysis of Mycobacterium leprae using skin biopsy tissues are essential for leprosy diagnosis and monitoring response to treatment. Although formalin fixation of patient tissues may not be ideal for molecular studies, biopsy samples are the most accessible materi...

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Detalles Bibliográficos
Autores principales: Chen, Xiaohua, Xing, Yan, He, Jun, Tan, Fuyue, You, Yuangang, Wen, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6774503/
https://www.ncbi.nlm.nih.gov/pubmed/31577795
http://dx.doi.org/10.1371/journal.pntd.0007731