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Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen

The impermeability of the luminal endothelial cell monolayer is crucial for the normal performance of the vascular and lymphatic systems. A key to this function is the integrity of the monolayer’s intercellular junctions. The known repertoire of junction-regulating genes is incomplete. Current perme...

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Detalles Bibliográficos
Autores principales: Simonneau, Claire, Yang, Junning, Kong, Xianguo, Kilker, Robert, Edelstein, Leonard, Fortina, Paolo, Londin, Eric, Horowitz, Arie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775082/
https://www.ncbi.nlm.nih.gov/pubmed/31578372
http://dx.doi.org/10.1038/s41598-019-50588-0