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Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen
The impermeability of the luminal endothelial cell monolayer is crucial for the normal performance of the vascular and lymphatic systems. A key to this function is the integrity of the monolayer’s intercellular junctions. The known repertoire of junction-regulating genes is incomplete. Current perme...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775082/ https://www.ncbi.nlm.nih.gov/pubmed/31578372 http://dx.doi.org/10.1038/s41598-019-50588-0 |