Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy

Aging is characterized by the progressive loss of physiological function in all organisms. Remarkably, the aging process can be modulated by environmental modifications, including diet and small molecules. The natural compound nordihydroguaiaretic acid (NDGA) robustly increases lifespan in flies and...

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Detalles Bibliográficos
Autores principales: Tezil, Tugsan, Chamoli, Manish, Ng, Che-Ping, Simon, Roman P., Butler, Victoria J., Jung, Manfred, Andersen, Julie, Kao, Aimee W., Verdin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775102/
https://www.ncbi.nlm.nih.gov/pubmed/31602311
http://dx.doi.org/10.1038/s41514-019-0037-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6775102/
https://www.ncbi.nlm.nih.gov/pubmed/31602311
http://dx.doi.org/10.1038/s41514-019-0037-7

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